The published NCCN Guideline has 3 parts: an algorithm that follows the step-by-step clinical decision-making process; a manuscript that discusses the data the recommendations are based on and the issues that were considered by the panel; and a bibliography. Each recommendation is categorized according to both the level of evidence supporting the recommendation and the degree of consensus among the Member Institutions that the recommendation is appropriate.Read more at Medscape

After reviewing the literature prior to July 2007, The American College of Preventive Medicine (ACPM) concluded that there is insufficient evidence to recommend routine prostate cancer screening with prostate-specific antigen (PSA) testing and digital rectal examination (DRE).[1] Rather, they recommended that clinicians have an annual discussion with their patients about the potential risks and benefits of prostate cancer screening and the limitations of the evidence currently available. Furthermore, routine testing is not even recommended for high-risk groups, such as men with a positive family history and African-American men, and if the patient defers to the physician concerning the decision to screen, testing should not be offered.Read more at Medscape

The updated NCCN Guideline, available on Medscape, was developed by a panel of 23 multidisciplinary prostate cancer experts from NCCN Member Institutions. The panel met in June 2007 to review evidence and formulate updated recommendations. All NCCN Guidelines are updated continuously, but at least once a year, with additional updates published when important new data that change practice standards are released. The update process includes extensive review of the current NCCN Guideline via institutional reviews at NCCN Member Institutions and review of recently published data, and formal input from the patient advocacy community. An agenda for the panel meeting is developed and panel members are assigned to present data regarding each agenda item. Relevant publications and results of the institutional review are distributed to NCCN Panel Members before the meeting. The published NCCN Guideline has 3 parts: an algorithm that follows the step-by-step clinical decision-making process; a manuscript that discusses the data the recommendations are based on and the issues that were considered by the panel; and a bibliography. Each recommendation is categorized according to both the level of evidence supporting the recommendation and the degree of consensus among the NCCN Member Institutions that the recommendation is appropriate.Read more at Medscape